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Resist Intensive Wrinkle-Repair Retinol Serum

Skin Type: All Skin Types
Concern: Acne | Anti-Aging | Break outs | Brown Spots | Rosacea | Sensitive Skin | Wrinkles
Size: 30 ml

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Availability: In stock

  • Works immediately and long term to improve multiple signs of aging
  • Unique blend of highly stabilized retinol, the gold standard dermatologists agree reduces wrinkles, as well as potent antioxidants to help repair and heal skin.
  • Stimulates healthy collagen production for firmer skin
  • Improves skin tone and texture so you’ll see a smooth, radiant glow
  • Can be worn under or over moisturizer, underneath sunscreen, and some foundations
  • Proven anti-irritants reduce redness and soothe sensitive skin
  • Helps fade red marks from past breakouts
  • Enhances makeup application by making skin’s surface extremely smooth
  • 100% fragrance- and colorant-free


prices are including VAT
  • Order a sample
  • 7 ml : €13.00
  • SAMPLE : €0.70
Resist Intensive Wrinkle-Repair Retinol Serum
fine product
Review by laura
this is a fine product. my skin has of course changed after started using pc products. I'm quite young and have blemish prone skin, but it is a good product. I would maybe recommend it to more mature skin because this really soften and help I think. My mom absolutely loved this (Posted on 16/03/2015)
Great product, great customer service!
Review by G
I got a free 7ml sample with my order and loved it! It moisturises well and has made my skin much clearer. It didn't cause me any breakouts, so I can use it every night without any extra moisturizer (I have combination skin). I ordered a full size product straight away so that I can take smaller bottle with me on vacations. However, full size bottle pump was not working properly so I contacted customer service, who replied really fast and sent me a new bottle.
All Paula's Choice products I have tried are great and also BIG THANKS TO CUSTOMER SERVICE! I am very pleased. :) (Posted on 02/03/2015)
I got the 7ml deluxe sample and loved it
Review by Joseph
I got the 7ml deluxe sample and loved it. If I had not been going to get the ultra light serum already would have grabbed the full size as well. (Posted on 31/12/2014)
Absolutely Amazing
Review by Monika
The only thing I can say is I really wish I would have found it sooner!

Thank you Paula's Choice for this and all other amazing products.
(Posted on 15/12/2014)
Silicone heavy
Review by Firefox7275
One 1ml sample lasted three applications (face and decollette) so a little goes a long way. Greasy on application, but the volatile silicones evaporate off fairly quickly leaving silky skin. I haven't experienced any irritation or adverse reaction even used twice a day or on irritated skin after microneedling. I will not purchase the full size because I am not keen on silicone heavy products. (Posted on 02/11/2014)
Resist serum
Review by Hanna
I had the same experience as some here, breakouts and worse wrinkles around the eyes. I have succesfully used the skin balancing serum for a year which also contains retinol so I have no idea what's causing the reaction. Customer Care: Thank you for your review. We are sorry to hear of your experience and discomfort. Although this is not a common response, we do understand that each customer is uniquely different in how they will respond to products or ingredients. We thank you for also contacting us by email regarding your experience.
(Posted on 01/10/2014)
Review by Alegría Shiau
I've been using RESIST Intensive Wrinkle-Repair Retinol Serum for 3 years and it really does work and makes my skin healthy and radiant. I'll continue using it!
(Posted on 08/06/2014)
Excellent for the wrinkles, I dont know about the eye area
Review by EIRINI
It changed very much the appearance of the nasolabial folds which were my thick wrinkles ( I have the nasolabial folds and the frown lines. This happened in 48 hours! The reason I didnt give 5 stars is because the eye area has shown a worse appearance I dont know why. I continue the treatment and I may come back with the results of longer use. I feel very happy that I bought this product because I never hoped that I could make those thick wrinkles look almost invisible. I believe this is a miracle product!!! I look younger in only 48 hours!!! ( I am 43 and I have combination skin). (Posted on 12/02/2014)
Causes breakouts
Review by luisa
had the same reaction as some people here. Still managing the breakouts it cause me. I had big expectations but did not worked for me. (Posted on 31/01/2014)
Causes breakouts
Review by pogacem
I've been trying to use this product for a couple of months now. Each time I apply it in the evenings, I get breakouts after 1-2 days. If I skip this product, the breakouts are disappearing. And coming back if I restart using the serum. (Posted on 21/01/2014)
Review by Alex
I had received a deluxe sample for this, and before it was over I had order the full size. I am early thirties with oily combination skin, and I always suffered from mild acne. This product worked miracles for me. I did not experience any break out period that people say that happens with retinol. I have been using it for almost 3 months now, and my acne has complete gone and my skin tone has tremendously improved. Perhaps it is worth mentioning that I alternate with the 2% BHA gel. In summary, I would recommend to try this if you are interested in a retinol product. (Posted on 05/01/2014)
The best thing ever!
Review by Toni
Been using this only five nights and can see a visibly difference in my skin! My skin is more radiant ja clearer and pores and blemishes has vanished. The most amazing thing is with the lines, they are already less vissible and the hole skin is firmer.
I like that its emollient, so i dont need moisturizer after this.
At nights i use pore reducing toner/resist toner and 2 % bha and this serum, mornings use same toners and bha, resist light serum and the new skin balancing spf 30 moisturizer.

(Posted on 27/07/2013)
Excellent - with a caveat
Review by Artemis
A little goes a long way and it makes my skin soft and radiant - just like all the other Paula's products I use. I do believe this product has helped A LOT with wrinkles around my eyes and also my decolletage, which was beginning to show a crease - I can see that it's literally stopped it from happening. So big rave for the results. The caveat I referred to is that I think it can give me spots around my mouth and on the chin. I try to counteract this by using it every other evening and generally avoiding the sensitive area. (Posted on 22/03/2013)
Excellent product
Review by Susie
This is a brilliant product which is very well packaged (for maintenance of the active ingredients as well as aesthetics). I have sensitive dry skin and rosacea and have found this to be absolutely excellent for my skin. It glides on smoothly and is quite quickly soaked up by the skin. I have been using PC products for years and have never had any problems with my skin (and most people think I look at least 10 years younger than I am - SPF 30 every day combined with antioxidant serum :-). Worth every penny! (Posted on 19/02/2013)
visible improvement
Review by Rochelle
This really is an exceptional product, the improvement in my skin is very visible but best of all it feels wonderful. I have not been economical in my use of this product and use it twice daily now, I will definitely be reordering! (Posted on 10/10/2012)
Resist intensive wrinkle-Repair
Review by Hetty
Sorry to say but my experience is exactly the same as Barbora.I tried it off and on for a few weeks but every time I had a very severe reaction. I am sure this was caused by the retinol. Customer Care : Thank you for your review. We are sorry to hear of your experience with this product. Although the response you mentioned is not common with this product, we understand that each person will respond differently to ingredients and products. We suggest trying the RESIST Super Antioxidant Concentrate Serum which does not contain retinol. (Posted on 10/09/2012)
very bad reaction
Review by Barbora
I was very excited when this product came out. I really like Paulas Choice products, mostly my favourites are the cleanser and toner for dry skin, the resist toner is excellent, resist moisturizer and few others. I have used them while still living in the USA quite a lot and on and off last few years. Always come back to them even when I am tempted to try other brands. I bought 2 of these when they first came out that is how excited I was. Figured it would do a lot of work in one product and make it all more simple for me. The first few times I used it, my face was a bit sensitive but nothing major, figured it is just the first retinol experience and it will pass. I used it only every few days to start slower. However, within the first week I developed some huge cystic acne spots - did not even know what they were since I never experienced this before. I kept using the product, did not even put two and two together. Things got way worse. I finally had to stop using everything on my face to calm it down a bit and slowly tried to fix my skin again. Being a big fan of Paula and given the fact I had two of these products, not totally cheap either, I tried it again - and two more times in about 3 months gaps. The same thing every time - huge cystic acne that really hurt. Gave up.
I am only writing this review to let others know that maybe it would be good to test on small patch of skin first for few days before using on your whole face. Everybody has a different skin so it may not be a problem for everybody but my experience was very bad and quite painful...Customer Care : Thank you for your review. We are sorry to hear of your experience with this product. While this response is not typical, we do understand that each customer is uniquely different in how they will respond to products or ingredients. This along with everyday environmental factors can sometimes play a part in how someone will ultimately respond to a product or combination of products.. Please contact customer care with any questions. (Posted on 05/09/2012)
Excellent Product
Review by Petra
This is the most fantastic product I have ever used! I use it at night and then apply the hydrating mask on top - my skin has never looked so perfect (hydrated, even skin tone, wrinkles less visible). After reading all the reviews on the US website I was slightly concerned that it may be too strong for my skin as I usually react to even basic exfoliating products, AHA etc but no reaction sofar. I used to spend an absolute fortune on skincare and my skin never looked this good -so 10 out of 10 for value for money / consistency of serum and most importantly result. (Posted on 25/04/2012)
my new favorite product
Review by Johanna
I love everything about it. The packaging is really chique, the serum smells lovely and is easy to use. The best bit is that it works wonders. I have been using other Resist products for a while, so my skin already looked very good for its 49 years of age but this serum adds more benefits: It plumps the skin even more and makes it look yet younger. What more to ask for? It is difficult to determine when to order a new bottle as it is impossible to tell how much of the product is used up. I would hate to run out of it so next time I will order two at once. (Posted on 24/03/2012)
Simply amazing stuff
Review by Lisa
I was already in love with the RESIST Super Antioxidant Concentrate Serum, but this product combines the best features of it with the power of retinol. I use it every night, starting with the weekly resurfacing treatment, then the retinol serum. Wow, if feels so great on my skin, and the best part is that in the morning I wake up with hardly any wrinkles on my brow! It definitely has a tightening effect on my face. And after only a week of using it I can already see some improvements in my wrinkles. My 47 year old face loves it. I was using a retinol product before this, but it used to irritate my skin so that I could only use it for a few days at a time then needed to take a break, but I don't have that with the resist retinol serum. The only problem is that I have other expensive night creams in my bathroom that I should use up, but every night I can't bear to put anything else but Paula's Choice serum on my face! Please never stop making this and thanks for keeping the price so reasonable. (Posted on 08/03/2012)

How should this product be used?

Smooth a few drops onto your face, neck, and eye area before moisturizing (or use alone). For daytime, follow with a product rated SPF 15 or greater. If alternating with Resist Super Antioxidant Concentrate Serum, we recommend applying the Intensive Wrinkle-Repair Retinol Serum at night, after cleansing, toning, and exfoliating with the Paula’s Choice products suitable for your skin type and concerns.
Additional info
  • Resist Intensive Wrinkle-Repair Retinol Serum can be used with any moisturizer, sunscreen, or topical prescription medicine, including prescription retinoids.
  • If worn during the day, be sure to protect your skin with a moisturizer or foundation rated SPF 15 or greater (and greater is better).
  • Works beautifully as a foundation primer (apply sparingly and allow to set before applying makeup).
  • Ongoing, substantiated research has shown that topical application of antioxidants will help reduce irritation and inflammation – two major problems for the health and short and long-term appearance of the skin.
  • Despite the many benefits retinol has, there is no single “best” anti-aging ingredient for skin. The retinol plus multiple antioxidants in this formula were chosen for their well-researched track records and history of being able to improve signs of aging. We’ve also included potent anti-irritants to ensure compatibility with sensitive skin.
  • What makes this product unique?

    Paula’s Choice Resist Intensive Wrinkle-Repair Retinol Serum is an exclusive formula that utilizes a proprietary blend of highly stabilized retinol, potent antioxidants, and skin-repairing ingredients. Its soothing, silky texture goes to work immediately to help skin of any age look and act younger. With ongoing use, you will see fewer wrinkles, smoother skin, and improved skin tone. This product is 100% fragrance- and colorant-free.

    Who is this product for?

    Anyone concerned with improving the appearance of aging skin and helping sun-damaged skin repair itself so it functions in a younger, healthier manner. Ideal for use with Paula’s Choice Resist line of anti-aging products. May be alternated with our best-selling Resist Super Antioxidant Concentrate Serum.
    Cyclopentasiloxane (silicone slip agent/suspending agent), Dimethiconol (silicone slip agent/suspending agent), Neopentyl Glycol Diheptanoate (skin-conditioning agent), Dicaprylyl Carbonate (emollient), Caprylic/Capric Triglyceride (skin-repairing ingredient), Phenyl Trimethicone (silicone slip agent), Squalane (emollient), Bisabolol (anti-irritanting agent), Tetrahexyldecyl Ascorbate (stabilized vitamin C/antioxidant), Retinol (antioxidant/cell-communicating ingredient), Tocotrienols (vitamin E-based antioxidant), Tocopherol (vitamin E/antioxidant), Lecithin (cell-communicating ingredient), Laminaria Ochroleuca (Kelp) Extract (anti-irritant), Avena Sativa (Oat) Kernel Oil (anti-irritant), Elaeis Guineensis (Palm) Oil (skin-repairing ingredient), Stearyl Glycyrrhetinate (licorice-derived anti-irritant), Hexylene Glycol (slip agent), Caprylyl Glycol (emollient), Ethylhexylglycerin (skin-conditioning agent), Phenoxyethanol (preservative).

    Sources to support the claims made for Resist Intensive Wrinkle-Repair Retinol Serum:

    Journal of the European Academy of Dermatology and Venereology, September 2011, ePublication; Experimental Dermatology, July 2011, pages 572–576; Fitoterapia, March 2011, pages 208–211; Lipids, September 2010, pages 833–841; Oxidative Medicine and Cellular Longevity, January-February 2010, pages 35–43; The Journal of Dermatological Treatment, May 2009, pages 276–281; Journal of the Indian Medical Association, April 2009, pages 219–222; American Journal of Clinical Dermatology, June 2008, pages 369–381; International Journal of Cosmetic Science, June 2008, pages 175–182; Journal of Dermatological Science, May 2008, pages 99–107; Archives of Dermatology, May 2007, pages 606–612; and Clinical Interventions in Aging, April 2006, pages 327-348.

    Is Resist Intensive Wrinkle-Repair Retinol Serum better than the other Paula’s Choice serums?

    Not better, just different. Think of it like broccoli and carrots: both are good for you but provide different nutritional benefits your body needs to be healthy. Resist Intensive Wrinkle-Repair Retinol Serum was formulated with a greater amount of retinol to provide a higher degree of wrinkle repair – but all Paula’s Choice serums contain an array of ingredients proven to help repair wrinkles and other signs of aging.

    Can I use two Paula’s Choice products with retinol, such as Resist Barrier Repair Moisturizer with Resist Intensive Wrinkle-Repair Retinol Serum?

    Yes, this is fine; however, if you noticed that applying such products at the same time causes signs of irritation (such as redness or flaking) it would be best to apply one in the morning and the other at night, or consider switching to Resist Super Antioxidant Concentrate Serum, which is retinol-free.

    Can I use Resist Intensive Wrinkle-Repair Retinol Serum with my prescription retinoid product (examples: Renova, Retin-A, generic tretinoin).

    Yes, but generally speaking, you don’t necessarily need to use retinol and a prescription retinoid. Many will do fine with one or the other, or you can apply the prescription retinoid at night and apply the retinol product during the day, always being sure to protect your skin with a product rated SPF 15 or greater. Keep in mind that using multiple retinoid products increases the risk of irritation, which is never the goal. With retinoids, more is not automatically better!

    Can I apply Resist Intensive Wrinkle-Repair Retinol Serum with a product medicated with benzoyl peroxide?

    Yes. For best results, apply the benzoyl peroxide product to breakout-prone areas, allow to dry, then follow with Resist Intensive Wrinkle-Repair Retinol Serum. Note that benzoyl peroxide should not be applied at the same time as the prescription retinoid tretinoin, as it renders this active ingredient ineffective. It does not appear to have this same effect on retinol.

    Can I layer Paula’s Choice serums? Do I need to do this?
    Yes, you can and it does not matter which serum is applied first. Experiment to see which order of serum application works best for you.
    No, you do not need to layer serums as every Paula’s Choice serum treats skin to an array of brilliant ingredients. But for those who desire to apply more than one of our serums at the same time, it is fine to do this after cleansing, toning, and exfoliating. Because layering two serums plus your daytime moisturizer may feel too heavy under makeup, we recommend those who wish to layer our serums do so at night.

    I keep depressing the pump, but no product is coming out.
    The pump is not broken as you might think, but it is a so called airless pump. This product is packaged in an airless pump dispenser which utilizes a vacuum system to dispense and keep the contents fresh. Airless packaging helps to keep air and contaminates out of the product, which enhances the formula's stability and effectiveness.

    When using your product for the first time, you may need to "prime" the dispenser. To prime, simply pump the dispenser slowly about 10-15 times. If the dispenser stops working at any time, simply repeat the "priming" step. Do not attempt to dismantle the package.
    We kindly request you to please try again. If the pump still isn’t working please contact us.

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