Do you have problems with your skin, such as scars, pigmentation, facial skin ageing or very dry skin? The Paula's Choice Clinical collection has been specially developed to effectively counteract these types of problems. The products contain only proven active ingredients that are aimed at restoring and maintaining your skin condition. Discover more


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  • NEW
    All Skin Types

    A powerful treatment with 1% retinol that firms skin, fades brown spots and smooths wrinkles.

    Free travel size Resist Anti-Aging Retinol Serum
    Free travel size moisturizer
  • All Skin Types

    Reduces fine lines, brightens and firms skin.

    Free travel size Resist Anti-Aging Retinol Serum
    Free travel size moisturizer
  • All Skin Types

    Our most advanced night cream with 5 ceramides, vitamin C and 0.1% retinol to tackle signs of ageing.

    Free travel size Resist Anti-Aging Retinol Serum
    Free travel size moisturizer
  • Dry skin

    Ultra-rich hydrating cream provides immediate relief for uncomfortably dry skin.

    Free travel size Resist Anti-Aging Retinol Serum
    Free travel size moisturizer
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Products from our clinical collection

Our Clinical products have been specially developed for persistent skin problems, such as red pimples, rosacea-prone skin, deep wrinkles or scars. The products include:

  • Clinical 1% Retinol Treatment
  • Clinical Ceramide-Enriched Night Cream
  • Clinical Ultra-Rich Night Cream
  • Clinical Body Butter

Clinical 1% Retinol Treatment
A light cream that quickly absorbs into your skin. The combination of a high concentration of retinol with antioxidants and soothing, skin-restoring ingredients stimulates cell renewal and gives you a more even skin tone.

Clinical Ceramide-Enriched Night Cream
This cream is a superstar when it comes to combatting skin ageing. It especially tackles fine lines and wrinkles thanks to our unique CollagenSupport Complex with hydrating ceramides. Moreover, it includes skin-restoring retinol for firmer skin and the antioxidant vitamin C that makes your skin radiant.

Clinical Ultra-Rich Night Cream
A rich cream that makes very dry and eczema-prone skin feel soft and smooth again. The nourishing ingredients strengthen the skin barrier. This prevents moisture loss and gives your skin the chance to recover.

Clinical Body Butter
Our creamiest lotion for (very) dry skin. Your skin will become supple and soft, without feeling sticky or greasy. The nourishing protective layer makes any dry and rough skin look much healthier again.

Maintain your skin condition

Sometimes your skin needs that extra TLC. Make sure you maintain your skin condition the best you can. Only then can you prevent skin problems. Having said that, it's important to first ascertain what type of skin you have. To make things easier, we've compiled a handy explanation for you. This way, you'll be able to determine your skin type and which Paula's Choice products are most suitable for you.

Buy Paula’s Choice Clinical

Do you have problematic skin yourself? Then we recommend purchasing products from Paula’s Choice Clinical collection. Order today and benefit from fast and inexpensive delivery. Are you ultimately unsatisfied with the product? Simply send the product back. Thanks to our 30-day money-back guarantee, we'll make sure to pay back the purchase price.

Truth in beauty

Our mission is to provide you with the right information about skincare, so that you can make the best product choices for your skin. Our products do what they promise and we want you to experience that for yourself that's why we offer a 30 day money-back guarantee. If you are not satisfied with your purchase, contact us within 30 days for a refund.

We are here to help you

Do you have questions about sensitive skin or about the products from our Calm collection? Contact our Customer Care team. Our skincare experts are on hand to help you find the best products for your skin.